Liver Organ Transplant
It has the capacity to eliminate the tissue and function damage that the liver suffers due to some factors under normal conditions, by renewing itself. In other words, it is one of the rare organs that can renew itself. However, in some cases, the capacity of the liver to regenerate itself is insufficient against the magnitude of the damage, and the liver may be irreversibly damaged.
Liver failure: Apart from hereditary abnormalities in children, liver failure occurs in two different ways in adults. The first of these is acute liver failure. It is an emergency picture that occurs suddenly due to a number of reasons (such as viral hepatitis, drugs, mushroom poisoning) in a person without any known liver disease and is characterized by almost complete loss of liver functions. The second cause of liver failure is chronic liver failure. In other words, it is cirrhosis. It is the irreversible failure of the liver as a result of prolonged exposure to various causes (hepatitis B and C viruses, alcohol, autoimmune diseases, Wilson`s disease, Budd-Chiari syndrome).
Organ transplantation: As in kidney failure, there is no dialysis-like support system for the liver to perform its functions. Therefore, if a patient develops liver failure, it means that it is life-threatening. In this case, the most effective and only treatment option is liver transplantation. While the probability of survival of these patients without liver transplantation is 10%, the probability of survival with transplantation increases to 90%.
Transplantation sources: Persons who donated organs, but who had brain death due to some reasons (such as traffic accident, brain hemorrhage, heart attack). The organ donor must not have liver, cancer or any contagious disease.
Is blood group and tissue compatibility necessary in transplantation? Blood group compatibility is essential between the donor and the patient to whom organ transplantation will be performed. However, the compatibility of the blood with the Rh factor is not sought.